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We retrospectively studied patients diagnosed with P. aeruginosa bloodstream infections (BSIs) in two Italian university hospitals. Risk factors for the isolation of multidrug-resistant (MDR) or non-MDR P. aeruginosa in blood cultures were identified by a case-case-control study, and a cohort study evaluated the clinical outcomes of such infections. We identified 106 patients with P. aeruginosa BSI over the 2-year study period; 40 cases with MDR P. aeruginosa and 66 cases with non-MDR P. aeruginosa were compared to 212 controls. Independent risk factors for the isolation of MDR P. aeruginosa were: presence of central venous catheter (CVC), previous antibiotic therapy, and corticosteroid therapy. Independent risk factors for non-MDR P. aeruginosa were: previous BSI, neutrophil count
Cambridge University Press
Publication date: 
1 Nov 2011

Mario Tumbarello, E Repetto, Enrico Maria Trecarichi, Camilla Bernardini, Gennaro De Pascale, A Parisini, Marianna Rossi, MP Molinari, Teresa Spanu, C Viscoli, Roberto Cauda, M Bassetti

Biblio References: 
Volume: 139 Issue: 11 Pages: 1740-1749
Epidemiology & Infection